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Glucagon-like peptide-1 is a hormone produced in the gut that travels through the bloodstream and attaches to a receptor found on the surface of cells mostly in the pancreas and the brain
Dosing is extrapolated from preclinical models [1] [6]
Klemets A et al
Capehorn MS, Catarig AM, Furberg JK et al (2020) Efficacy and safety of once-weekly semaglutide 1.0mg vs once-daily liraglutide 1.2mg as add-on to 1-3 oral antidiabetic drugs in subjects with type 2 diabetes (SUSTAIN 10)
Bone loss caused by iron overload in a murine model: importance of oxidative stress
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