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According to a meta-analysis of 11 clinical trials (791 patients), ALCAR is superior to placebo in reducing depressive symptoms

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1995 Oct;80(10):2987-92

362,366 Multimodal therapeutic approaches combining pharmacotherapy, CBTs, and neuromodulation techniques are being explored to alleviate neuropathic pain and improve patient outcomes

It activates melanocortin-4 receptors in the hypothalamus, triggering dopamine release in the mesolimbic pathway (the brain's reward and desire circuitry) and activating oxytocinergic neurons that drive genital arousal in both sexes