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Further, patients should be informed that, given the chronic nature of IC/BPS, the typical course involves symptom exacerbations and remissions
J.van den BogaerdeJ.SamuelD.et al (2017)
6.2 Need for IGF-1R targeting agents with higher specificity The drug candidates targeting IGF-1R signaling that are under clinical trial investigation include: IGF ligand inhibitors, which are monoclonal antibodies targeting IGF-1/2
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