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377 The TAMRAD phase 2 clinical trial enrolled postmenopausal patients with HR+ metastatic breast cancer who had failed aromatase inhibitor therapy, comparing tamoxifen combined with the mTOR inhibitor everolimus versus tamoxifen monotherapy

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Potential indications include: Chronic weight management Type 2 diabetes Metabolic dysfunction-associated steatohepatitis (MASH / NASH) Other metabolic diseases Yao Pharma will continue its ongoing Phase 1 trial in Australia , after which Pfizer takes full control of global development and commercialization

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