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While more research is needed in this area, a study looking at GLP1 receptor agonist use and opioid overdose risk in patients with type 2 diabetes and opioid use disorder (OUD) found that semaglutide was associated with reduced opioid overdose risk in patients with comorbid T2D and OUD
GLP-1 receptors demonstrate widespread but selective distribution throughout the central nervous system
Oct 2021;48(5):803-808
Consider semaglutide alternatives If your semaglutide headaches or other side effects become too much, talk to your healthcare provider about whether an alternative treatment could be a better fit for you
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