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Challenges in losing weight through diet and exercise alone

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While patients typically experience efficient weight loss, they might feel lethargic and fatigued while taking the medication because of GI side effects and reduced calorie intake

In select cases, probiotics may be incorporated into a routine to support digestive comfort as the gut adapts to new intake patterns, though individual response can vary

Octreotide therapy of pediatric hypothalamic obesity: a double-blind, placebo-controlled trial