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This study below, published in 1967 carried out trials to determine how long cyanocobalamin and hydroxocobalamin B12 injections lasted before excretion in urine but you can see from their summary that it would be unreliable to assume that one size fits all
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Once they have got their gut microbes and hormones in better balance and optimised DAO production, then other than being mindful of eating too many high histamine foods, they should only experience mild reactions that can be managed by occasional supplements and/or medications
Clin Virol
2023;151(2):e2022060640
