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Free cytoplasmic Ca 2+ concentrations were estimated for individual cells from background-subtracted fluorescence using the equation of Grynkiewicz [26] assuming a K d of 224 nmol/l

Most digestive side effects, including heartburn, typically improve with continued treatment or dose adjustment

Agents called keratolytic, such as lactic acid, salicylic acid, benzoyl peroxide, ammonium lactate, and urea at concentrations less than 40%, do not have any direct effect on keratin instead they hydrate the stratum corneum, allowing proteases to resume normal function and desquamation to proceed more normally than in dry conditions

PMID: 2645190

If the product has a specified duration of use, rinse off after this time has elapsed