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Appetite, Weight, and Metabolic Effects The gap between these two drugs is widest in the metabolic domain

Low Blood Sugar Hypoglycemia This side effect can occur when in combination with other glucose control medications

Animal models have demonstrated that GLP-1 RAs reduce drug-seeking behavior and attenuate conditioned place preference for substances such as alcohol, nicotine, and cocaine (32)

Researchers also compared patients whose HS symptoms got better while on semaglutide to patients whose HS symptoms stayed the same or got worse

Unlike Mounjaro, however, Zepbound is FDA-approved to support weight management for people living with obesity or overweight who have at least one weight-related condition, such as type 2 diabetes, high cholesterol, or hypertension (high blood pressure)