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In rodent models, blocking NNMT with 5-Amino-1MQ led to lower fat mass, more energy burn, and better insulin response all without cutting calories

These include: Having trouble absorbing B12 from food because of conditions like pernicious anemia or stomach problems

For the analysis of lipids in the serum from WT, Gclc L-KO, Nrf2 L-KO, and L-DKO mice, the methods were the same with the following exceptions: MS2 scan conditions were applied in positive mode, the scan range was from m/z 120-1000, and the resolution was 120,000 for MS

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