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Specifically, the side chain of R283 6.55 moves towards F279 6.51 and H280 6.52 due to steric effects with the octanoyl chain of ghrelin or the phenyl group of ibutamoren (Fig

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Nat Commun 9(1):4462 Nakamoto N, Sasaki N, Aoki R, Miyamoto K, Suda W, Teratani T et al (2019) Gut pathobionts underlie intestinal barrier dysfunction and liver T helper 17 cell immune response in primary sclerosing cholangitis

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Its extended half-life of approximately 4.7 days is attributed to its structural design, discussed in the large molecule conjugation section of this paper

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Energy failure and abnormal mitochondrial dynamics are central components of ischemic injury [8]

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