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Br J Pharmacol (2013) 170:1092101.10.1111/bph.12352 24 ChoiSLeeMShiuALYoSJHalldenGAponteGW
This was first suggested for the GLP-1R agonists exendin-4 and liraglutide when it was shown that the suppression of food intake that they cause upon systemic administration is prevented or attenuated when the GLP-1R antagonist exendin-9 is centrally administered in rats [7] and when central GLP-1Rs are deleted in mice [8]
The relationship between the blood-brain-barrier and the central effects of glucagon-like Peptide-1 receptor agonists and sodium-glucose Cotransporter-2 inhibitors
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139.5lbs = 18lbs] Lost in a little over 4 months" loading="lazy"/>
![F/26/5'6” [157>129=28] turns out watching what you eat and running everyday works! : r/progresspics](https://i.redd.it/5vbxhp6nhj721.jpg)
132lbs = 25lbs] weight loss progress!! looking at my back makes me so happy : r/progresspics" loading="lazy"/>
![F/28/5'8” [307 lbs > 150 lbs= 157 lbs lost] (2 years) On the left, I had been crying for hours before the photo was taken because I felt so worthless. On the](https://i.redd.it/v2zf95cjv3wa1.jpg)
![M/28/5'9” [240 lbs > 157 lbs] (5 years) ish : r/Brogress](https://preview.redd.it/m-28-59-240-lbs-157-lbs-5-years-ish-v0-042jctu2dkaf1.jpg?width=640&crop=smart&auto=webp&s=4a3c49cf0c105f830a14bd8d20cfd10213d8a45d)
