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The cyclization is formed via a lactam bridge between the side chains of Asp and Lys, constraining the peptide backbone into a stable, bioactive conformation

Molecular mechanism of valine and its metabolite in improving triglyceride synthesis of porcine intestinal epithelial cells

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These drugs are part of an emerging class of nutrient-stimulated hormone-based therapeutics that act as incretin mimetics, targeting G-proteincoupled receptors such as GLP-1, glucose-dependent insulinotropic polypeptide (GIP), and glucagon, which are crucial in body fat and energy balance regulation

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