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Hyperglycemia-induced mTOR upregulation leads to blood-brain barrier disruption and endothelial dysfunction, and contributes to tau hyperphosphorylation and amyloid- aggregation in Alzheimers disease (Van Skike and Galvan, 2018
& Coulson, I
Biomed Pharmacother 163:114825 Funding Open access funding provided by The Science, Technology & Innovation Funding Authority (STDF) in cooperation with The Egyptian Knowledge Bank (EKB)
and many other regions and are supplied strictly for laboratory research purposes
2 Materials and methods 2.1 Study design and participants The present study is a retrospective analysis of follow-up clinical data
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