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In the pivotal STEP 1 trial, patients receiving semaglutide 2.4mg weekly achieved average weight loss of 14.9% over 68 weeks
It found that patients with diabetes who were prescribed semaglutide, which is marketed as Wegovy and Ozempic, were about four times more likely to be diagnosed with non-arteritic anterior ischemic optic neuropathy (NAION), an eye condition that is painless but cannot be treated or cured
Neither medication is recommended for: Anyone with known allergies to the active ingredients People with a history of medullary thyroid cancer or MEN2 syndrome Individuals with severe GI conditions Pregnant or breastfeeding individuals Side Effects to Expect (and Manage) Both Semaglutide and Tirzepatide are considered safe when used under the care of a healthcare provider
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Macrophage recruitment in obese adipose tissue
