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HIF-1 activation not only regulates the expression of glycolysis-related enzymes, such as hexokinase and lactate dehydrogenase but also enhances the expression of glucose transporters (GLUT), thereby increasing glucose uptake by tumor cells ( ID significantly impacts cellular energy metabolism by modulating key signaling pathways such as AMP-activated protein kinase (AMPK) and the mechanistic target of rapamycin (mTOR) (64)
Interaction of BSA/AuNCs with either the metallic core, the stabiliser or the linkage between these two, might interfere with the fluorescence properties 68
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Examples of side effects seen with GLP-1s are: Gastro-intestinal ( most common) Constipation, diarrhea, vomiting Headaches, fatigue Mood disturbance Loss of muscle, bone density, strength, and balance #Kidney, vision, allergic reactions (#less common) More side effects are being proclaimed almost daily
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