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Tirzepatide works the same way
The STEP 1 trial for semaglutide (the active ingredient in Ozempic and Wegovy) enrolled 1,961 participants with similar characteristics
Phase 3 data: TRIUMPH-4 The TRIUMPH-4 trial focused on participants with osteoarthritis and demonstrated an average weight loss of 71.2 pounds along with significant improvements in joint pain and function
Semaglutide is currently being investigated in two large phase III clinical trial programs for treating obesity: the STEP program, which aims to obtain regulatory approval for semaglutide as an anti-obesity drug and is evaluating cardiovascular outcomes in 17,500 patients
However, the benefits related to body weight usually disappear as well
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