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In particular, DAS and its metabolites have been found to inhibit CYP2E1 activity in vitro (56, 57) and when administered orally at high doses to animals (58, 59)
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This is particularly important if you take insulin or sulfonylureas Monitor for worsening gastrointestinal symptoms, especially during Wegovy dose escalation Keep a symptom diary to identify any new or worsening side effects If you have diabetes, you may need more frequent blood glucose monitoring When to seek immediate medical advice: Severe or persistent abdominal pain (potential pancreatitis) Signs of hypoglycaemia that do not resolve with usual measures Severe nausea, vomiting, or diarrhoea leading to dehydration Allergic reactions (rash, swelling, difficulty breathing) Any unexplained symptoms after starting the combination For urgent concerns, contact NHS 111 or 999 in an emergency
Cleveland Clinics health articles are based on evidence-backed information and review by medical professionals to ensure accuracy, reliability and up-to-date clinical standards
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