If you have severe nausea, vomiting, dehydration, stomach pain, very rapid weight loss, blood sugar concerns, or trouble eating enough, contact your healthcare provider.
Metformin: Metformin is an oral medication approved to treat type 2 diabetes, but can be prescribed off-label for weight loss
GIP/GLP-1s The newest class of drugs that treat both type 2 diabetes and obesity work with both of the main digestive hormones that tell your body to make insulin: GLP-1 and glucose-dependent insulinotropic polypeptide (GIP)
It is important to note however that the vast majority of GBM have wild-type IDH1 and still have dysregulation of HIF-1 and VEGF, indicating that this key process occurs most commonly via mechanisms other than those involving the presence of 2-HG
Diabetologia 55 (4), 948958