This week-long half-life is why weekly dosing works
Additionally, research to examine the newer and more potent weight-loss GLP-1 receptor agonists, semaglutide (Ozempic/Wegovy, Novo Nordisk) and tirzepatide (Mounjaro/Zepbound, Eli Lilly), would be particularly important.
After 7 days, intragastric administration of 20 mg/kg SFN did not significantly affect the composition of intestinal bacteria
Proc Natl Acad Sci U S A 99:1190813 Harvey CJ, Thimmulappa RK, Singh A, Blake DJ, Ling G, Wakabayashi N, Fujii J, Myers A, Biswal S (2009) Nrf2-regulated glutathione recycling independent of biosynthesis is critical for cell survival during oxidative stress
The standard recommendation is to wait one week (7 days) between your last tirzepatide injection and your first semaglutide injection