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New results released this week from the SURMOUNT-5 clinical trial comparing tirzepatide (Zepbound) to semaglutide (Wegovy) are closely aligned to Truveta Researchs GLP-1 comparative effectiveness study, initially shared more than a year ago on November 27, 2023 and published earlier this year in JAMA Internal Medicine

In one study, patients who received Semaglutide GLP-1 lost an average of 15% of their body weight over 68 weeks, compared to a placebo group that lost only 2.4% of their body weight

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For longer use, periodic breaks and routine health check-ups are advisable