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Such a non-protein cofactor is known as a "prosthetic group." R -lipoic acid functions as a prosthetic group for the biological activity of the following multienzyme complexes: The glycine cleavage system that catalyzes the decarboxylation of glycine coupled with the addition of a methylene group (-CH 2 ) to tetrahydrofolate to form 5,10-methylene tetrahydrofolate, an important cofactor in the synthesis of nucleic acids ( Figure 3 )
Lyophilized powder may be stored at room temperature for short periods but should be kept at -20 degrees C for long-term storage
Research on exercise-induced oxidative stress demonstrates how physical exertion can drive muscle damage and pain, a mechanism that may share similarities with the debilitating fatigue and deep muscle aches patients experience daily
