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MOTS-C offers a more separate research question than cagrilintide, but it also has a much weaker human outcome base

PMID 32966863

The expression of FOSL1 in the culture medium for all the samples were undetectable

Tendon and ligament fibroblast cultures examining outgrowth rate, collagen organization, and growth-factor receptor expression after mechanical or chemical injury

Results A cross-species transcriptional atlas of the caudal brainstem To identify species-specific transcriptional response to cagrilintide signalling in the DVC, we treated 30 diet-induced obese (DIO) mice and 42 DIO rats with either a single dose or seven daily doses of cagrilintide or vehicle (subcutaneous or s.c.)