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Semaglutide and tirzepatide have broadly similar safety profiles, both dominated by gastrointestinal side effects, though tirzepatide's GI effects can run slightly higher at its top dose
The evidence base for most of these peptides in humans is thin
28 : 537548 Harsing LGJ, Sershen H, Toth E, Hashim A, Ramacci MT, Lajtha A
She cautions that sterility and safety are not guaranteed: If a compounding pharmacy tells you that theres a certain amount of the active drug in an injection, that cant be verified independently. She warns, be really careful about the potential for fraud. Practices that choose to prescribe or dispense compounded semaglutide should weigh the risks and conduct a careful vetting process