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These changes dramatically reduce how well IGF-binding proteins can grab IGF-1 LR3
Use of GLP-1 analogue drugs is associated with benefits but also health risks The use of glucagon-like peptide-1 receptor agonists (GLP-1RAs), used to treat diabetes and obesity, may be associated with a wide range of health effects, both positive - such as a reduced risk of cardiometabolic disorders - and negative - an increased risk of gastrointestinal conditions or hypertension
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Some examples of GLP-1 receptor agonists include: Semaglutide, known under the brand names of Ozempic, Rybelsus, and Wegovy Liraglutide, known under the brand name Saxenda Tirezepitide (Mounjaro), a GLP-1 receptor agonist that also activates GIP receptors in the body These powerful drugs help millions with insulin resistance and obesity, but gastrointestinal side effects are relatively common
