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This disrupts the tight junction structure, thereby increasing BBB permeability and facilitating the infiltration of inflammatory cells and harmful substances

Therapeutic potential of brain-derived neurotrophic factor (BDNF) and a small molecular mimics of BDNF for traumatic brain injury

2.3.1 Background ALS is a serious and progressive disease that damages both the upper and lower motor neurons, which are the nerve cells that control voluntary muscle movement

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however, larger studies are still needed to confirm these effects