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The glyoxalase system in health and disease
Knobloch M, Pilz G-A, Ghesquire B, Kovacs WJ, Wegleiter T, Moore DL, Hruzova M, Zamboni N et al (2017) A fatty acid oxidation-dependent metabolic shift regulates adult neural stem cell activity
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70 This sustained imbalance manifests as ER stress, oxidative damage, mitochondrial dysfunction, and chronic low-grade inflammation, all of which accelerate disease progression
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