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Diabetes Metab Syndr Obes (2021) 14:295572
Datos toxicolgicos preclnicos: Los estudios de toxicidad aguda y subaguda en la rata no han evidenciado mortalidad ni toxicidad orgnica significativa, incluso a dosis ampliamente superiores a las dosis teraputicas (hasta 100 veces la dosis eficaz)
Semple et al., 2010) indicated that within 24 h of the trauma, polymorphonuclear leukocytes and cytokines released inflammatory agents like IL-6, IL-1, and TNF-
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