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Pharmacokinetics: Scopolamine is rapidly and fully distributed into the CNS where it has greater effects than most other antimuscarinics
The authorized generic (AG) strategy (e.g., Pfizers Lipitor defense) is designed to cannibalize and conquer: by launching an AG the same day the first-to-file generic enters, the innovator captures approximately 70% of the generic markets revenue and systematically devalues the 180-day exclusivity prize that generic companies have been racing to win
Testing enables precision medicine rather than one-size-fits-all dosing
Selection of patients : It may be that benefits are strongest in those with early metabolic dysfunction, mild cognitive impairment, or early Alzheimers disease, rather than in advanced dementia
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