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Firstly, activated NF-B and NLRP3 inflammasome in DN promotes inflammation and increases fibronectin and collagen deposition in kidney, 41,42 leading to thickening glomerular basement membrane, glomerular sclerosis, podocyte damage, and ultimately kidney fibrosis

Investigations into the machinery at the mitochondria-endosome membrane contact site are ongoing, aiming to elucidate the mechanism of mitochondria and endosome interaction and the role of the endocytic system in sustaining mitochondrial homeostasis

Selenium: Synergistic selenium is required for glutathione peroxidase activity

Ginseng saponin enriched in rh1 and rg2 ameliorates nonalcoholic fatty liver disease by inhibiting inflammasome activation

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