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Both semaglutide and tirzepatide are GLP-1 receptor agonists proven to support weight loss in clinical trials, but they differ in mechanism and individual response patterns

However, those who had a greater decrease in waist circumference with semaglutide had a larger reduction in major adverse CV event risk

Whether its looser clothing or better energy levels, the shift becomes clearer

Avoid in pregnant or breastfeeding individuals due to a lack of appropriate data

If the pen was frozen, exposed to temperatures above 86F for extended periods, or stored at room temperature beyond manufacturer specifications, it should be discarded regardless of appearance