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Oral PUVA is now no longer preferred due to various adverse effects associated with oral psoralens, such as gastralgia, nausea, risk of severe generalized phototoxicity, and photocarcinogenesis
This delay can alter the timing of peak drug concentration and, in some cases, the overall absorption amount
In people with T2D, retatrutide (0.5 to 12 mg) led to substantial reductions in bodyweight and HbA1c compared to both placebo and dulaglutide 1.5 mg in a phase 2 trial [67]
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