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Widespread vasoconstriction was observed after inhibiting nNOS (Fig

Finally, each section includes separate presentations of the results from the meta-analyses

FIGURE 5 2.4.1 Vascular remodeling In DR, the RhoA/ROCK signaling pathway is activated by high glucose, which leads to endothelial dysfunction, breakdown of the blood-retinal barrier (BRB), and capillary leakage