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Oncogene 36 , 60306040 (2017)

Symptoms include: Persistent fatigue and lack of motivation Decreased libido or erectile dysfunction Loss of muscle mass and strength Weight gain and slower metabolism Mood changes, irritability, and poor focus Reduced bone density A meta-analysis published in Clinical Endocrinology confirmed that TRT significantly increases lean body mass and decreases fat mass in hypogonadal men (Corona et al., 2016)

10.1038/cddis.2012.156 Cell Death Dis

Once-weekly dosing options

Step 1: Wash hands thoroughly with soap and water Step 2: Clean the vial stopper with an alcohol swab Step 3: Draw the appropriate dose into your syringe Step 4: Clean the injection site with alcohol and let it dry Step 5: Pinch skin to create a fold of subcutaneous tissue Step 6: Insert needle at 45-degree angle into the skin fold Step 7: Inject slowly over 5 to 10 seconds Step 8: Withdraw needle and apply light pressure if needed Local vs